Which antidepressant was repackaged and renamed Sarafem to help women deal with PMDD?

• A. Nexium
• B. Vioxx
• C. Prozac
• D. Xanax

Answer: (C)

This question tests how an existing antidepressant can be repackaged and marketed for a specific condition like PMDD. The antidepressant Prozac contains the active ingredient fluoxetine, an SSRI that helps elevate serotonin levels in the brain to improve mood and reduce irritability and other premenstrual mood symptoms. The drug was repackaged and renamed Sarafem to target PMDD specifically, with labeling and marketing directed at women experiencing these symptoms. The same medication thus serves both as Prozac for depression and as Sarafem for PMDD, illustrating how a single antidepressant can be positioned for different conditions based on clinical use and branding. The other substances listed are not antidepressants used for PMDD: Nexium treats acid reflux, Vioxx is a pain reliever that was withdrawn from the market, and Xanax is a benzodiazepine used for anxiety.