Which of the following is a narcotic analgesic?

• A. Oxycodone
• B. Diphenhydramine
• C. Aspirin
• D. Marijuana

Answer: (A)

Oxycodone is an opioid analgesic, a narcotic. It works by binding to mu-opioid receptors in the brain and spinal cord to dampen pain signals, and it’s used for moderate to severe pain. This class of drugs carries a risk of dependence, tolerance, and serious side effects like respiratory depression, which is why it’s specifically labeled as a narcotic analgesic.

Diphenhydramine is an antihistamine with sedative effects and does not serve as a primary pain reliever, so it isn’t a narcotic analgesic. Aspirin is an NSAID that reduces pain and inflammation by blocking prostaglandin production, not by acting on opioid receptors. Marijuana provides pain relief through cannabinoids rather than opioids, so it isn’t classified as a narcotic analgesic.